![]() The second phase takes place in the liver. A plus sign next to the number “” means that the information is found within the full scientific study rather than the abstract. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at that each number in parentheses is a clickable link to peer-reviewed scientific studies. Our goal is to not have a single piece of inaccurate information on this website. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists.Īll of our content is written by scientists and people with a strong science background. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. We believe that the most accurate information is found directly in the scientific source. The linear model reduces the number of unnecessary blood samples from 201 to 69, and has an RMSE that is lower than the specified error of the TcB device, and can therefore be accepted as a valid model to predict TSB values.SelfDecode has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed. The error of the measurement data ranges from 30.2 to 85.2 μmol L−1, depending on the body measurement location. The data used to train the models contains a mix of measurements with and without phototherapy. The specified error of the TcB measurement device for preterm infants without phototherapy is 27.4μmolL−1, and 39.0μmolL−1 after phototherapy. The root mean square error (RMSE) of the linear regression model is 21.9μmolL−1, and that of the decision tree is 30.4μmolL−1. Two models have been realized: a linear regression model and a decision tree. Machine learning is applied to map the TcB measurements more accurately to a TSB value. This data includes TcB measurements on five body locations and patient characteristics, along with the actual TSB measurements. This study uses the data of n = 101 newborn infants that are preterm (median gestational age: 30.5 weeks, range: 28.0 to 35.7). Therefore it is of interest to increase the accuracy of a TcB measurement. This group is also more susceptible to jaundice. However, TcB measurements are less accurate, especially for preterm infants. This technique is preferred because it is non-invasive, cheaper and faster than the traditional method. A non-invasive technique to determine the bilirubin levels is through the skin, using a transcutaneous bilirubinometry (TcB) device. This causes a high strain on the newborn. The traditional method to determine the TSB is by analysing blood samples in a laboratory. ![]() These bilirubin levels, total serum bilirubin (TSB), need to be determined frequently, in order to detect early onset of jaundice and start treatment. High levels of bilirubin in the bloodstream are the main cause of this. Jaundice is a serious disease which affects mostly newborn infants.
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